{"Absorption, Distribution and Excretion":"ORAL RETENTION OF CETYLPYRIDINIUM CHLORIDE GIVEN AS 1 MIN MOUTH RINSE OF 10 ML OF 2.2 MMOL SOLN WAS 65% OF ADMIN DOSE.","Adverse Effects":"Neurotoxin - Other CNS neurotoxin","Aliases":["hexadecylpyridinium chloride","Pristacin","Cepacol","Ceprim","Cetamium","Dobendan","Pyrisept","Aktivex","Biosept","1-Cetylpyridinium chloride","Ceepryn chloride","Cepacol chloride","Quaternario CPC","Acetoquat CPC","Intexsan CPC","Swabettes Hoechst","Ammonyx CPC","Medilave","Cetyl pyridinium chloride","Merocet","N-Hexadecylpyridinium chloride","N-Cetylpyridinium chloride","Ceeprin chloride","Cetylpyridini chloridum","Fixanol C","1-Palmitylpyridinium chloride","Cetylpyridinii chloridum","Cetylpyridinium chloride anhydrous","Cloruro de cetilpiridinio","Chlorure de cetylpyridinium","Cetilpiridinio cloruro","Dtxsid6041761","NSC-14864","Dtxcid4021761","Chebi:32915","Ceepryn","Pyridinium, 1-hexadecyl-, 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Fresh Mint","Anhydrous, Cetylpyridinium Chloride","Chloride Anhydrous, Cetylpyridinium","antigingivitis/antiplaque mouth rinse","CPC 1000 Pre and Post Teat Dip","Suction Swab with Corinz Oral Rinse","TheraBreath Healthy Gums Oral Rinse","Crest Pro-Health Intense Clean Mint","Crest Pro-Health Intense Fresh Mint","Denti Whoo Bubble Concentrated Gargle","PerCara Oral Health Rinse Fresh Mint","Cetylpyridinium chloride 0.05%","CPC 0.05% Antiplaque/Anti-gingivitis","Crest Pro-Health Gum and Breath Purify","Oral B Gum Detoxify Special Care Rinse","Parodontax Active Gum Health Clear Mint","Discount drug mart mint mouthwash","Colgate Total Active Prevention Spearmint","Crest Pro Health Gum plus Bacteria Guard","SmartMouth Mouthwash Clinical DDS Formula","Suction Toothbrush with Corinz Oral Rinse","Colgate Total Active Prevention Gum Health","Colgate Total Active Prevention Peppermint","SmartMouth Clinical Gum and Plaque Formula","Colgate Total Advanced Gum Health Mouthwash","Crest Pro-Health Breath Purify and Gum Care","SmartMouth Advance Clinical DDS Formula Mint","Oral B Plaque Defense Special Care Oral Rinse","Colgate Total 12 Hr Pro-Shield Spearmint Surge","Colgate Total Advanced Pro-Shield Peppermint Blast","Colgate Total Advanced Pro-Shield Spearmint Surge","Equate Healthy Gums Clean Mint Breath Oral Rinse","Qcare oral cleansing and suctioning system","Crest Pro-Health Pro Active Defense Whole Mouth Clean","QCare Petite Size Oral Cleansing and Suctioning System","Scope All Day CPC Antigingivitis/Antiplaque Mouthwash","Crest Pro-Health Multi-Protection Refreshing Clean Mint","Hello Peace Out Plaque peace out, plaque antigingivitis","Scope Get Fresh CPC Antigingivitis/Antiplaque Mouthwash","SmartMouth SmartMouth Gum Health Zinc Activated Formula","Parodontax Active Gum Health Daily Mouthwash Breath Freshener","Scope All Day CPC Antigingivitis/Antiplaque Mouthwash All Day","Toothette Oral Care Single Use System with Antiseptic Oral Rinse","204-593-9","QCare Oral Cleansing and Suctioning System compatible with 0.12% Chlorhexidine Gluconate (CHG) Oral Rinse","D9OM4SK49P","NB-002","1-Hexadecylpyridinium chloride","Tserigel","Cetylpyridinium chloride","Mfcd00011731","Cetylpyridinium","1-Hexadecylpyridin-1-ium;chloride","Caswell No. 166A","HSDB 38","Einecs 204-593-9","NSC 14864","EPA Pesticide Chemical Code 069160","Unii-6br7t22e2s","AI3-15070","NB 002","Cetyl-pyridinium chloride","hexadecylpyridine, chloride","Schembl4763","Chembl34833","Spectrum1500169","orb1300767","orb3025803","1-hexadecylpyridin-1-iumchloride","HMS501B08","HY-B1464R","HMS1920M13","HMS2091A20","HMS3652F05","HMS5082L04","Pharmakon1600-01500169","HY-B1464","NSC14864","Tox21_301296","CCG-39719","EBC-26657","MSK163017","NSC756673","s4172","SBB080799","Akos005267197","Cetylpyridinium (chloride)","KS-5309","Wln: t6kj a16 \u0026 q \u0026 g","Ncgc00094618-01","Ncgc00094618-02","Ncgc00257543-01","AC-32490","Cas-123-03-5","DB-041704","A5161","CS-0013168","H0078","NS00093500","SW222237-1","En300-23845","F20369","F863111","Q418318","Sr-05000001582","Sr-05000001582-1","Z89264780","1-Hexadecylpyridinium chloride;Cetylpyridinium chloride anhydrous;Pyridinium, 1-hexadecyl-, chloride;CPC"],"Associated Disorders and Diseases":"Contact dermatitis, allergic [Category: Skin Disease]","CAS":"123-03-5","Chemical Classes":"Nitrogen Compounds -\u003e Quaternary Amines","ChemicalClasses":[],"Chirality":"achiral","Classes":["Antiseptic"],"Color/Form":"White powder","Decomposition":"When heated to decomposition it emits very toxic fumes of /nitrogen oxides and hydrogen chloride/.","Drug Warnings":"QUATERNARY AMMONIUM ANTISEPTICS ... APPLIED TO SKIN ... FORM FILM UNDER WHICH BACTERIA MAY REMAIN VIABLE EVEN THOUGH OUTER SURFACE OF FILM IS BACTERICIDAL. SINCE CETYLPYRIDINIUM CHLORIDE IS INACTIVATED BY SOAPS, SOAP USED IN PRE-OPERATIVE TREATMENT OF SKIN MUST BE THOROUGHLY REMOVED ... BEFORE APPLICATION OF ANTISEPTIC.","Erowid Experience Reports":[],"Esters":[],"European Community (EC) Number":"204-593-9","Formating":[],"HeavyAtomCount":23,"IUPACName":"1-hexadecylpyridin-1-ium chloride","InChI":"InChI=1S/C21H38N.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22;/h15,17-18,20-21H,2-14,16,19H2,1H3;1H/q+1;/p-1","InChIKey":"YMKDRGPMQRFJGP-UHFFFAOYSA-M","Interactions":"AVOID ALCOHOL, WHICH HAS BEEN SHOWN TO INCREASE THE ORAL TOXICITY OF ... CETYL PYRIDINIUM CHLORIDE ... .","KEGG Entries":[{"Id":"D01062","Interactions":[],"Synonyms":["Cetylpyridinium chloride","Cetylpyridinium chloride hydrate","Sprol"]}],"MeSH Headers":[{"Id":"M0003969","Link":"https://id.nlm.nih.gov/mesh/M0003969.html","Name":"Biosept","Ref":59},{"Id":"M0003970","Link":"https://id.nlm.nih.gov/mesh/M0003970.html","Name":"Ceepryn Chloride","Ref":60},{"Id":"M0003972","Link":"https://id.nlm.nih.gov/mesh/M0003972.html","Name":"Cetamium","Ref":61},{"Id":"M0003974","Link":"https://id.nlm.nih.gov/mesh/M0003974.html","Name":"Cetylpyridinium Chloride","Ref":62},{"Id":"M0003975","Link":"https://id.nlm.nih.gov/mesh/M0003975.html","Name":"Dobendan","Ref":63},{"Id":"M0003976","Link":"https://id.nlm.nih.gov/mesh/M0003976.html","Name":"Pristacin","Ref":64},{"Id":"M0003977","Link":"https://id.nlm.nih.gov/mesh/M0003977.html","Name":"Pyrisept","Ref":65},{"Id":"M0585641","Link":"https://id.nlm.nih.gov/mesh/M0585641.html","Name":"Cetylpyridinium Chloride Anhydrous","Ref":66},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":67},{"Id":"M0001330","Link":"https://id.nlm.nih.gov/mesh/M0001330.html","Name":"Anti-Infective Agents, Local","Ref":88},{"Id":"M0006090","Link":"https://id.nlm.nih.gov/mesh/M0006090.html","Name":"Detergents","Ref":89}],"MeSH Pharmacological Classification":[{"Id":"M0001330","Link":"https://id.nlm.nih.gov/mesh/M0001330.html","Name":"Anti-Infective Agents, Local","Ref":88},{"Id":"M0006090","Link":"https://id.nlm.nih.gov/mesh/M0006090.html","Name":"Detergent","Ref":89}],"Mechanism of Action":"MODE OF ACTION ... NOT YET FULLY UNDERSTOOD BUT HAS BEEN ASCRIBED TO ... THE DENATURING OF LIPOPROTEIN COMPLEXES, \u0026 POSSIBLY OTHER ACTIONS. /QUATERNARY AMMONIUM COMPD/","Melting Point":"80 °C","MolecularFormula":"C\u003csub\u003e21\u003c/sub\u003eH\u003csub\u003e38\u003c/sub\u003eClN","MolecularWeight":"340.0 g/mol","Non-Human Toxicity Values":"LD50 Rat oral 200 mg/kg","Physical Description":"Other Solid","PubChemId":31239,"Records":{"UNII":{"Impurities":[]}},"RefChem":"5661","RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Cetylpyridinium_chloride","Name":"Cetylpyridinium chloride","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/31239","Name":"Cetylpyridinium chloride","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=123-03-5","Name":"Cetylpyridinium chloride","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/6BR7T22E2S","Name":"Cetylpyridinium chloride","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID6041761","Name":"Cetylpyridinium chloride","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 31239, cetylpyridinium chloride. Accessed May 11, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/31239\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/31239\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Cetylpyridinium chloride. UNII: 6BR7T22E2S. Global Substance Registration System. Accessed May 11, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/6BR7T22E2S\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/6BR7T22E2S\u003c/a\u003e"],"SMILES":"CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1.[Cl-]","SaltData":[],"Salts":[],"Solubility":"Very soluble in water, chloroform","StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 243.28 38.854\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h244v39H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m242.242 20.802-13.198 7.621M229.044 28.423l-13.199-7.619M215.845 20.804l-13.197 7.622M202.648 28.426l-13.199-7.619M189.449 20.807l-13.198 7.622M176.251 28.429l-13.199-7.619M163.052 20.81l-13.197 7.621M149.855 28.431l-13.199-7.618M136.656 20.813l-13.198 7.621M123.458 28.434l-13.199-7.618M110.259 20.816l-13.197 7.621M97.062 28.437l-13.199-7.619M83.863 20.818 70.666 28.44M70.666 28.44l-13.199-7.619M57.467 20.821l-13.198 7.622M44.269 28.443l-9.51-5.49\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m25.859 35.155 3.842-10.565M24.049 32.998l3.36-9.242\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m29.701 24.59-1.921 5.283M27.409 23.756l-1.68 4.621\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m25.859 35.155-15.008 2.646\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.053 26.117 9.798 11.684M3.825 25.628l7.989 9.527\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.053 26.117 5.211-14.331\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M21.272 9.14 6.264 11.786M20.309 11.786 8.074 13.943\"/\u003e\u003c/g\u003e\u003cpath d=\"M28.23 17.437 21.272 9.14\" class=\"bond\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M33.011 23.274h-.721l-2.619-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.715l2.607 4.054h.03l-.018-.327-.024-.476q-.006-.262-.006-.482v-2.769h.578zM34.687 18.23h.818v.293h-.818v.846h-.297v-.846h-.818v-.293h.818v-.85h.297z\"/\u003e\u003c/g\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M43.31 1.498q-.786 0-1.238.53-.453.524-.453 1.447 0 .91.417 1.446.423.53 1.268.53.322 0 .607-.053.292-.06.566-.143v.535q-.274.102-.566.149-.291.054-.696.054-.744 0-1.25-.31-.5-.309-.75-.875-.25-.571-.25-1.339 0-.744.267-1.31.274-.566.804-.881.53-.322 1.28-.322.78 0 1.351.286l-.244.524q-.226-.101-.506-.184-.274-.084-.607-.084m2.757 4.423h-.602V.706h.602zM40.403.56v.293H38.47V.56z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m34.759 22.953 4.755 2.745M34.759 22.953l4.755 2.745M28.23 17.437l-3.479-4.148M28.23 17.437l-3.479-4.148\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":null,"Therapeutic Uses":"Anti-infective Agents, Local","Title":"Cetylpyridinium chloride","Toxicity Data":"LC50 (rat) = 90 mg/m3/4h","UNII":"6BR7T22E2S","Wikipedia":"Cetylpyridinium_chloride","XLogP":null}